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ea0020p560 | Neuroendocrinology, Pituitary and Behaviour | ECE2009

Ovariectomy causes hippocampal neuronal loss and cognitive dysfunction and restored by Ginkgo biloba extract EGb761 in rats

Koike Koji , Takuma Kazuhiro , Hoshina Yuki , Suzuki Nobutaka , Inoue Masaki , Yamada Kiyofumi

Combination of ovariectomy (OVX) and chronic restraint stress causes cognitive dysfunction and reduces hippocampal CA3 neurons in female rats and that estrogen replacement suppresses the OVX/stress-induced behavioral and morphological changes. Aim of this study is to exsamine the effect of Ginkgo biloba extract (EGb 761) on the cognitive dysfunction and neuromorphological change in OVX/stress-subjected rats. Female Fisher 344 rats were randomly divided into three groups...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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